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Cholinergic Urticaria - Cholinergic Urticaria information
What are Cholinergic Urticaria
Cholinergic Urticaria is a rare skin disorder that is a localized (cutaneous) form of mastocytosis.Cholinergic Urticaria most often affects infants, with the first patches appearing at a few months of age.
Urticaria and angioedema are commonly classified by duration.
In Cholinergic Urticaria, one can demonstrate the presence of mast cells by rubbing one of the brown patches. Within a few minutes, the rubbed area becomes reddened, swollen and itchy. This is known as Dariers sign, and confirms the presence of mastocytosis. In Cholinergic Urticaria, the rash consists of reddish-brown spots that turn into hives when they are rubbed hard or scratched. Sometimes the spots will blister.
Cholinergic Urticaria Cause
Cholinergic Urticaria is one of several forms of mastocytosis, which is caused by excessive numbers of inflammatory cells (mast cells) in the skin. Here are the list of some causes:
- excessive numbers of inflammatory cells (mast cells) in the skin
- systemic mastocytosis (involvement in organs other than the skin)
- headache
- diarrhea
- a rapid heartbeat
- even fainting .
Cholinergic Urticaria Symptom
Swelling of deeper layers of the skin, angioedema, commonly accompanies Cholinergic Urticaria. Here are the list of Cholinergic Urticaria Symptom.
- Diarrhea
- Fast heart rate
- Headache
- Fainting
Cholinergic Urticaria Treatment Antihistamines may relieve some of the histamine-induced symptoms such as itching and flushing.
Patients with Cholinergic Urticaria should avoid aspirin, codeine, opiates, procaine, alcohol. polymyxin B, hot baths, and vigorous rubbing after bathing and showering. These can release histamine which can cause itching, flushing and hives.
Potent steroid creams applied for several months under occlusion can reduce itching and unsightliness, but the patches tend to recur within a few months. Topical steroids are only suitable for limited areas in Cholinergic Urticaria.
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